Ken Shapiro is a former serial entrepreneur and now advises successful entrepreneurs, founders and CEOs of rapidly growing companies on their personal financial issues related to their families, strategic business exit planning and inter-generational wealth planning. His wife Patricia was diagnosed with rectal cancer in 2017. Ken dug deeply into colorectal cancer, he travelled the world meeting the very top doctors, researched every appropriate clinical trial he could find and convinced his wife’s doctors at MSK to combine unique experimental treatments that he pulled together from collaboration between cross-institutional specialists. This helped, but was not enough. From this Ken learned that beyond front line chemo there is no very effective treatment for metastatic colorectal cancer. Ken therefore became determined to make a difference and achieve success against this cancer in his lifetime.