Publications

Pembrolizumab for previously treated, microsatellite instability–high/mismatch repair–deficient advanced colorectal cancer: final analysis of KEYNOTE-164

February 24th, 2023

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Impact of genetic variants involved in the lipid metabolism pathway on progression free survival in patients receiving bevacizumab-based chemotherapy in metastatic colorectal cancer: a retrospective analysis of FIRE-3 and MAVERICC trials

February 4th, 2023

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An atlas of substrate specificities for the human serine/threonine kinome

January 11th, 2023

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Bintrafusp Alfa: A Bifunctional Fusion Protein Targeting PD-L1 and TGF-β, in Patients with Pretreated Colorectal Cancer: Results from a Phase I Trial

December 28th, 2022

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HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses

December 16th, 2022

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Strategies to overcome DC dysregulation in the tumor microenvironment

October 6th, 2022

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Charge-based interactions through peptide position 4 drive diversity of antigen presentation by human leukocyte antigen class I molecules

July 27th, 2022

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Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma

July 1st, 2022

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Pre-treatment serum albumin and mutational burden as biomarkers of response to immune checkpoint blockade

April 7th, 2022

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Spatial CRISPR genomics identifies regulators of the tumor microenvironment

March 14th, 2022

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Exhausted T cell phenotypes depend on TCR signal strength

February 22nd, 2022

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Oncolytic measles vaccines encoding PD-1 and PD-L1 checkpoint blocking antibodies to increase tumor-specific T cell memory

November 29th, 2021

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A Decade of Cancer Discovery

November 4th, 2021

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Improved prediction of immune checkpoint blockade efficacy across multiple cancer types

November 1st, 2021

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New interpretable machine-learning method for single-cell data reveals correlates of clinical response to cancer immunotherapy

October 27th, 2021

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Publications by BreakBio team members and advisors

Pembrolizumab for previously treated, microsatellite instability–high/mismatch repair–deficient advanced colorectal cancer: final analysis of KEYNOTE-164

Impact of genetic variants involved in the lipid metabolism pathway on progression free survival in patients receiving bevacizumab-based chemotherapy in metastatic colorectal cancer: a retrospective analysis of FIRE-3 and MAVERICC trials

An atlas of substrate specificities for the human serine/threonine kinome

Bintrafusp Alfa: A Bifunctional Fusion Protein Targeting PD-L1 and TGF-β, in Patients with Pretreated Colorectal Cancer: Results from a Phase I Trial

HLA-I immunopeptidome profiling of human cells infected with high-containment enveloped viruses

Strategies to overcome DC dysregulation in the tumor microenvironment

Charge-based interactions through peptide position 4 drive diversity of antigen presentation by human leukocyte antigen class I molecules

Reversal of viral and epigenetic HLA class I repression in Merkel cell carcinoma

Pre-treatment serum albumin and mutational burden as biomarkers of response to immune checkpoint blockade

Spatial CRISPR genomics identifies regulators of the tumor microenvironment

Exhausted T cell phenotypes depend on TCR signal strength

Oncolytic measles vaccines encoding PD-1 and PD-L1 checkpoint blocking antibodies to increase tumor-specific T cell memory

A Decade of Cancer Discovery

Improved prediction of immune checkpoint blockade efficacy across multiple cancer types

New interpretable machine-learning method for single-cell data reveals correlates of clinical response to cancer immunotherapy

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Publications by BreakBio team members and advisors

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