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Publications by BreakBio team members and advisors
Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability–High/Mismatch Repair–Deficient Metastatic Colorectal Cancer: KEYNOTE-164
November 14th, 2019
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Evolutionary divergence of HLA class I genotype impacts efficacy of cancer immunotherapy
November 7th, 2019
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Using parallelized incremental meta-docking can solve the conformational sampling issue when docking large ligands to proteins
September 5th, 2019
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CCR5 status and metastatic progression in colorectal cancer
July 13th, 2019
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Oncogenic LncRNA downregulates cancer cell antigen presentation and intrinsic tumor suppression
June 3rd, 2019
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Addition of Platinum Derivatives to Fluoropyrimidine-Based Neoadjuvant Chemoradiotherapy for Stage II/III Rectal Cancer: Systematic Review and Meta-Analysis
May 11th, 2019
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Immunogenic neoantigens derived from gene fusions stimulate T cell responses
April 22nd, 2019
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The evolving landscape of biomarkers for checkpoint inhibitor immunotherapy
March 19th, 2019
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Neoantigen vaccine generates intratumoral T cell responses in phase Ib glioblastoma trial
December 19th, 2018
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Acquired mechanisms of immune escape in cancer following immunotherapy
November 22nd, 2018
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A cloning and expression system to probe T-cell receptor specificity and assess functional avidity to neoantigens
November 1st, 2018
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Peptide vaccine formulation controls the duration of antigen presentation and magnitude of tumor-specific CD8+ T cell response
April 11th, 2018
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General Prediction of Peptide-MHC Binding Modes Using Incremental Docking: A Proof of Concept
March 12th, 2018
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Patient HLA class I genotype influences cancer response to checkpoint blockade immunotherapy
February 1st, 2018
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Glioblastoma stem cell-derived exosomes induce M2 macrophages and PD-L1 expression on human monocytes
January 16th, 2018
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